In the neighbourhood (Kiez) there are renovated and unrenovated old buildings and gap-filling new buildings. The main shopping street in Charlottenburg Südwest is Wilmersdorfer Straße with a shopping centre, department stores, smaller shops and cafés. Between Stuttgarter Platz and Schillerstraße, Wilmersdorfer Straße is designed as a pedestrian zone. On the nearby Karl-August-Platz there is a weekly market every Wednesday and Saturday.

The northern part of Wilmersdorfer Strasse is the founding cell of Charlottenburg. Here there are still partly single-storey buildings from the 17th century. The area is characterised by a high proportion of old buildings and neighbourhood shops. The Schloßstraße with some museums is quiet and leads to Schloss Charlottenburg with its park.

The Klausenerkiez, also called Dankelmannkiez, has a well-preserved old building fabric, most of which has been renovated. Families are in good hands here. There are many playgrounds and schools, ecological projects and even a goat farm. The neighborhood is also traffic-calmed, and good local recreation opportunities such as the Schloßpark Charlottenburg and Lietzenseepark are nearby.

Witzleben is the area around the Lietzensee and is bordered by the Stadtbahn, the Ringbahn, the Kaiserdamm and the Windscheid- and Suarezstraße. Thanks to Lietzensee and Lietzenseepark - a green oasis in the neighbourhood - Witzleben is a sought-after residential area.

The southwest of Charlottenburg around Stuttgarter Platz and Adenauerplatz is a simple, quiet residential area with a mixture of old and new buildings. Many young families live here. There are a few green spaces, playgrounds, small shops and cafés. At Stuttgarter Platz - affectionately called Stutti - you can go out. Especially in the western part there are some restaurants and bars.

Kalowswerder, around Mierendorffplatz, is an island, bordered to the south and west by the Spree, to the east by the Charlottenburg connecting canal, to the north by the railway line and the Westhafen canal respectively. The Mierendorff district is characterised by a mixture of old buildings and social buildings, gas and power station. On the banks of the Spree, the Austria Park with its sunbathing lawn, park benches, playground, sports field, rock garden and rose garden invites you to relax.

An der Helmholtzstraße und Franklinstraße im Nordosten Charlottenburgs an der Grenze zu Moabit gibt es überwiegend einfache Altbauten. Die TU Berlin ist dort ansässig. Im Bereich zwischen Landwehrkanal und Spreebogen ist die Spreestadt Charlottenburg entstanden, ein neues Stadtquartier für Dienstleistung, Gewerbe und Wohnen auf dem ehemaligen Industrie- und Gewerbegelände. Mit 250.000 qm ist das Gelände dreimal so groß wie die Potsdamer-Platz-Bebauung.